In an effort to make sure it doesn’t start going the way of MySpace, especially with Hulu on the rise, YouTube is trying something a little new. On November 22, YouTube will be webcasting live from San Francisc, CA. The show is set to be huge with appearances from Will.I.Am, Katy Perry, and famous-through-YouTube Esmée Denters. YouTube’s first live webcast is also going to feature several users who have become relatively famous through the video-sharing site. So far, there are about 50 talents and entertainers on the bill for what looks to be a pretty exciting show. Other acts and personalities will include Adam and Jamie Hyneman from the show Mythbusters where they’ll perform one of their famous experiments live. Should the venture prove to be a hit, which it undoubtedly will, it could be a new shift in focus for YouTube and a way to stop on top of competing video-hosting sites.